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英文名称 Anti-ApoO/Apolipoprotein O
中文名称 载脂蛋白O抗体
别 名 0610008C08Rik; 1110019O03Rik; Apolipoprotein O; APOO; APOO_HUMAN; FAM121B; Family with sequence similarity 121B; MGC130105; MGC130106; MGC4825; My025; MYO25; OTTHUMP00000023073; Protein FAM121B; RP23-272D10.2.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep
产品类型 一抗
研究领域 肿瘤 心血管 细胞生物 新陈代谢
蛋白分子量 predicted molecular weight: 20kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human ApoO/Apolipoprotein O
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Apolipoproteins are a family of fatty-acid binding proteins that transport fat through the bloodstream in the form of lipoproteins. ApoO (Apolipoprotein O), also known as FAM121B or My025, is a 198 amino acid single-pass membrane protein that belongs to the apolipoprotein family. Expressed ubiquitously with particularly high expression in diabetic heart tissue, apoO functions to promote the transport of cholesterol from macrophage cells and may be involved in regulatory mechanisms that protect lipid accumulation within the heart. ApoO is present in high density lipoproteins (HDLs) and low density lipoproteins (LDLs) and is secreted by an MTP (microsomal triglyceride transfer protein)-dependent mechanism. Two isoforms of apoO exist due to alternative splicing events.
Function : Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL. May be involved in myocardium-protective mechanisms against lipid accumulation.
Subcellular Location : Membrane. Secreted.
Tissue Specificity : Expressed in all tissues examined. Up-regulated in diabetic heart.
Post-translational modifications : O-glycosylation; glycosaminoglycan of chondroitin-sulfate type.
Similarity : Belongs to the apolipoprotein O family.
Database links : UniProtKB/Swiss-Prot: Q9BUR5.1
中文名称 载脂蛋白O抗体
别 名 0610008C08Rik; 1110019O03Rik; Apolipoprotein O; APOO; APOO_HUMAN; FAM121B; Family with sequence similarity 121B; MGC130105; MGC130106; MGC4825; My025; MYO25; OTTHUMP00000023073; Protein FAM121B; RP23-272D10.2.
详细介绍：
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep
产品类型 一抗
研究领域 肿瘤 心血管 细胞生物 新陈代谢
蛋白分子量 predicted molecular weight: 20kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human ApoO/Apolipoprotein O
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相关资料：
产品介绍 Apolipoproteins are a family of fatty-acid binding proteins that transport fat through the bloodstream in the form of lipoproteins. ApoO (Apolipoprotein O), also known as FAM121B or My025, is a 198 amino acid single-pass membrane protein that belongs to the apolipoprotein family. Expressed ubiquitously with particularly high expression in diabetic heart tissue, apoO functions to promote the transport of cholesterol from macrophage cells and may be involved in regulatory mechanisms that protect lipid accumulation within the heart. ApoO is present in high density lipoproteins (HDLs) and low density lipoproteins (LDLs) and is secreted by an MTP (microsomal triglyceride transfer protein)-dependent mechanism. Two isoforms of apoO exist due to alternative splicing events.
Function : Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL. May be involved in myocardium-protective mechanisms against lipid accumulation.
Subcellular Location : Membrane. Secreted.
Tissue Specificity : Expressed in all tissues examined. Up-regulated in diabetic heart.
Post-translational modifications : O-glycosylation; glycosaminoglycan of chondroitin-sulfate type.
Similarity : Belongs to the apolipoprotein O family.
Database links : UniProtKB/Swiss-Prot: Q9BUR5.1
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